Lubricating Microneedles for Osteoarthritis | Sustained Drug Delivery Breakthrough
1. Introduction Osteoarthritis is one of the most prevalent degenerative joint diseases, causing pain, stiffness, and reduced mobility in millions of people worldwide. Recent advances in biomedical research have focused on creating minimally invasive, effective, and long-acting treatments to improve patient outcomes. The lubricating microneedle system with multistage sustained drug delivery represents a breakthrough in targeted therapy, combining innovative drug-release technology with a gentle, patient-friendly delivery platform that addresses both lubrication and anti-inflammatory needs for long-term joint health. 2. Microneedle Design and Engineering The microneedles used in this system are carefully engineered to penetrate the skin painlessly while delivering therapeutic agents directly to the synovial region. Their structure includes lubricating properties that reduce friction and tissue damage, ensuring comfort and improving compliance in repeated treatments. 3. Multista...

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