world Skincare Innovation

   Introduction Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferation of keratinocytes and dysregulated immune responses. Emerging evidence suggests that dietary factors, particularly protein intake, may modulate inflammatory pathways. This research explores how varying levels of dietary protein influence both cutaneous and systemic inflammation in mice with acute experimental psoriasis, providing insight into the intersection of nutrition, immunology, and dermatological disease mechanisms. Experimental Design and Methodology This study utilizes an acute murine psoriasis model to evaluate the impact of controlled dietary protein variations on inflammatory severity. Mice are divided into low-protein, normal-protein, and high-protein diet groups prior to psoriasis induction. Clinical scoring, histopathological analysis, cytokine profiling, and systemic biomarker assessment are performed to determine how protein intake alters inflammatory progre...

  We are proud to announce that [Dr. Kai an Chuang] has been honored at the World Skin Care Innovation Awards 2026 for outstanding contributions to skincare research and innovation. Their groundbreaking work in [specific field – e.g., skin barrier science / anti-aging research / dermatological technology] is setting new global standards in skincare excellence. 👏 Congratulations on this remarkable achievement and for advancing the future of skin health worldwide.  Visit: https://skincareaward.com/  Nominate Now: https://w-i.me/skin #ResearchAwards #ScienceAwards #worldresearchawards #AcademicAwards #GlobalResearchAwards #SkinCareInnovation #DermatologyResearch #BeautyScience #SkinScience #CosmeticInnovation #GlobalAwards  

   Introduction The study explores the sebum-regulating, anti-inflammatory, and lipid-restoring efficacy of isorhamnetin extracted from Opuntia ficus-indica through a randomized double-blind clinical trial. As excessive sebum production and chronic inflammation are central to acne and barrier dysfunction, plant-derived flavonoids have emerged as promising therapeutic candidates. This research investigates the translational potential of isorhamnetin as a multifunctional dermatological active ingredient supported by clinical validation. Phytochemical Profile and Mechanism of Isorhamnetin Isorhamnetin is a methylated flavonol known for its antioxidant and anti-inflammatory properties. Extracted from Opuntia ficus-indica , it modulates inflammatory cytokines, reduces oxidative stress, and influences sebocyte activity. Mechanistically, it downregulates pro-inflammatory mediators such as IL-6 and TNF-α while enhancing epidermal lipid synthesis pathways, contributing to improved bar...

  Introduction The periocular skin is anatomically unique due to its thin epidermis, reduced sebaceous gland density, and high vascularization, making it particularly susceptible to aging, pigmentation, and inflammatory conditions. Recent advances in in vivo non-invasive high-resolution imaging technologies have revolutionized the evaluation of this delicate region. This introduction outlines the clinical significance of periocular assessment and the growing need for objective, reproducible, and quantitative imaging-based diagnostic methods in dermatological and aesthetic research. Optical Coherence Tomography in Periocular Skin Evaluation Optical coherence tomography (OCT) provides cross-sectional, micrometer-resolution imaging of skin layers without biopsy. Research highlights its ability to measure epidermal thickness, collagen density, and dermal–epidermal junction integrity in the periocular region. Studies demonstrate its value in monitoring photoaging, treatment response ...

  1. Introduction Chronic photoaging represents a major dermatological concern characterized by progressive collagen degradation, reduced dermal thickness, and structural disorganization caused by long-term ultraviolet (UV) exposure. Unlike intrinsic aging, photoaging accelerates extracellular matrix breakdown through oxidative stress and inflammatory cascades. Recent research has focused on botanical bioactives such as black ginseng extract as potential modulators of collagen synthesis and dermal repair mechanisms in human skin. 2. Molecular Pathways of Collagen Degradation in Photoaged Skin Ultraviolet radiation stimulates reactive oxygen species (ROS) production, activating transcription factors such as AP-1 and NF-κB. These pathways upregulate matrix metalloproteinases (MMP-1, MMP-3, and MMP-9), which degrade type I collagen in the dermis. Chronic exposure disrupts fibroblast function and reduces procollagen synthesis, resulting in visible wrinkling and loss of elasticity. U...

  Introduction Kaposi Sarcoma (KS) is a vascular neoplasm frequently associated with immunological dysregulation and human herpesvirus-8 infection, presenting commonly as cutaneous lesions. In women, disease presentation may involve cosmetically sensitive areas, necessitating targeted therapeutic strategies. High-Dose-Rate (HDR) brachytherapy offers localized radiation with high precision and limited toxicity. This mono-institutional research series evaluates the clinical role of HDR brachytherapy in managing skin Kaposi Sarcoma in women, emphasizing treatment efficacy, safety, and cosmetic outcomes. Clinical Characteristics and Patient Selection This research topic explores demographic distribution, lesion localization, staging parameters, immune status, and inclusion criteria for women treated with HDR brachytherapy. It analyzes tumor thickness, lesion multiplicity, anatomical considerations, and prior therapies. Understanding patient selection criteria is critical to optimizi...