Exploring Acne Treatments: From Pathophysiology to Breakthrough Therapies in Modern Dermatology
Pathophysiological Mechanisms of Acne Development This topic explores the underlying biological processes involved in acne formation, including sebaceous gland hyperactivity, follicular hyperkeratinization, bacterial colonization, and inflammatory responses. Special emphasis is placed on the role of Cutibacterium acnes and its interaction with the immune system, helping researchers identify critical pathways that can be targeted for therapeutic intervention. Role of Hormones and Genetics in Acne Progression Hormonal fluctuations, particularly androgens, play a crucial role in stimulating sebum production and influencing acne severity. This research examines genetic predispositions and endocrine factors that contribute to acne susceptibility, providing insights into personalized treatment approaches and predictive diagnostics for individuals at higher risk. Advances in Conventional Acne Treatments Traditional acne treatments such as retinoids, antibiotics, and benzoyl peroxide...